ABSTRACTThe incidence of isoniazid (INH) resistant Mycobacterium tuberculosis is increasing globally.This study aimed to identify the molecular mechanisms behind the development of INH resistance in M.tuberculosis strains collected from the same patients during the standard course of treatment.Three M.tuberculosis strains were collected from a pati

The shield method is a common construction method for pipelines crossing rivers.Here, with the pipeline installation in Heilongjiang Shield Crossing Project of China-Russia Eastern Gas Pipeline as an example, the curve laying technology of large-diameter pipelines was elaborated.In the project, the tunnel axis was designed as a straight downslope a

The small molecule, thiazolidinedione-8 (S-8) was shown to impair biofilm formation of various microbial pathogens, including the fungus Candida albicans and Streptococcus mutans.Previously, we have evaluated the specific molecular mode of S-8 action against C.albicans biofilm-associated pathogenicity.In this study we investigated the influence of

AbstractWe report the case of a 38-year-old man, who developed cutaneous metastases in the left inguinal groove 15 years after curative gastrectomy for advanced gastric adenocarcinoma.Histopathologic examination revealed poorly differentiated adenocarcinoma cells.They were stained positive for villin, CDX-2, CKpan (AE1/ AE3), CEA, CK8/18, CK19, Abo

Taking as its starting point hookah the debate on the contribution made by participation to the quality of democracy, this article seeks to situate the issue within the context of Portugal.In the last 40 years, Portugal has experienced three critical junctures: the April revolution, EU membership and the economic crisis.Revolutionary ideals were co